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AACR 2024, April 5-10, San Diego, CA

Meet us at AACR 2024 in San Diego, California

The annual meeting of the American Association for Cancer Research (AACR) in San Diego on April 5-10 is just around the corner, and we're thrilled to be a part of it.   

We have some exciting things planned with our Phenoplex software that we can't wait to share with you. 

Interactive Multiview Analysis: review and analyze multiple images simultaneously within Phenoplex 

With multiplex image analysis, keeping an overview over your data set can be difficult. Semiautomatic steps like setting thresholds for biomarker positivity which requires acessing each individual image can be time consuming.   

  • How are cell populations distributed across your data set?   
  • How consistent is the stain intensity for the different layers?  
  • How to be sure that artifacts or false positives do not reduce the result quality?  

Phenoplex is our complete workflow for all your multiplexed image analysis needs. With the new interactive Multiview Analysis you can now review and analyze several slides at the same time. No matter if you are reviewing the layers, setting thresholds for positivity or reviewing the results using our interactive plots – the Multiview Analysis allows you to be more effective and more confident in getting the data you need for your research. 

Get a demo at Visiopharm's booth #646

Solutions for all plex levels  

No matter your imaging system and plex level of your assay, Phenoplex has the solution for all spatial biology assays: Fully automated phenotyping for up to 8 Markers and user-guided phenotyping for 8-40+ markers.  

Confused about which markers make up which phenotype of cell? Have a look at our new immune oncology PD-L/1 landscape sheet and grab one at our booth #646.

thumbnail-phenoplextable-Immune-oncology-PD-L1-landscape_1
Immune oncology PD-L/1 landscape
Are you spending a lot of time on the ROI/AOI selection step in your GeoMx workflow? 

Visiopharm and NanoString are launching a new integration that will automate and simplify your region selection for GeoMx using AI-driven image analysis.   

 AI will reduce the time to determine interesting areas from the GeoMx image or use an adjacent tissue section stained by H&E. An added advantage is to use Visiopharm’s software to unlock data in the GeoMX image.  

Check out our joint poster #27 with NanoString and ProPath UK, to see examples of the workflow for reading GeoMx images, importing the ROI regions, performing cell segmentation, and phenotyping them for further transcriptome analysis.  

Posters being presented at AACR

A deep learning approach to guide acquisition region selection for imaging mass cytometry

Session Date and Time: Tuesday April 9, 2024, 9:00 AM - 12:30 PM
Session Title: In Vivo Imaging and Anatomical and Molecular Pathology

Presenters/Authors: Fabian Schneider, Smriti Kala, Sam Lim, Clinton Hupple, Nina Lane

Read the abstract

Automating a spatial profiling workflow to explore the effects of hypoxia in the tumor microenvironment in head and neck cancer 

Session Date and Time: Tuesday April 9, 2024, 1:30 PM - 5:00 PM
Session Title: Spatial Resolution of the Tumor Microenvironment

Presenter/Authors: David Mason, Kyla Teplitz, James Robert Mansfield, Kelly Hunter

Read the abstract

HOST-Factor: A comprehensive platform for single-cell highplex immunofluorescence staining, digital imaging, spatial mapping, and quantitative analysis of the tumor microenvironment

Session Date and Time: Tuesday April 9, 2024, 1:30 PM - 5:00 PM
Session Title: Spatial Resolution of the Tumor Microenvironment

Authors: Janusz Franco-Barraza, Fabian Schneider, Rasmus Norré-Sørensen, Rasmus Ahrenkiel-Lyngby, Caneta Brown1, Dan Winkowski, James Robert Mansfield, Edna Cukierman

Read the abstract

Comparison the results from PD-L1 IHC and PD-L1 multiplex immunofluorescence for the prediction of anti-PD-1 immunotherapeutic response

Session Date and Time: Tuesday April 9, 2024, 1:30 PM - 5:00 PM
Session Title: Predictive Biomarkers 5

Presenter/Authors: H. Sun, X. Liu, T. Jiao, Q. Guo, H. Du, S. Han, L. Zhu, Z. Zhang, Y. Kong, N. Li

Read the abstract

 

Determining tumour homologous recombination repair status in PDX and clinical samples using automated RAD51 scoring

Session Date and Time: Monday April 8, 2024, 9:00 AM - 12:30 PM
Session Title: Predictive Biomarkers 1

Presenter/Authors: J. Robertson, J. Ashton, G. N. Jones, G. Mills, T. Y. Ozmen, M. J. Rames, S. Park, P. Waring, N. Lukashchuk, E. Harrington

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Digital pathology workflow: Building a bridge for translational biomarker development in humanized mice

Session Date and Time: Tuesday April 9, 2024, 1:30 PM - 5:00 PM
Session Title: Detection, Imaging, and Pathology

Presenter/Authors: M. Hakkarainen, T. Bragge, J. Rytkönen, E. Oswald, J. B. Schueler

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Single-cell spatial proteomic analysis to explore the spatial heterogeneity of desmoplastic small round cell tumors

Session Date and Time: Tuesday Apr 9, 2024, 1:30 PM - 5:00 PM
Session Title: Pediatric Cancer Microenviroment, Tumor Heterogeneity, and Targeted Therapeutics

Presenter/Authors: D. Truong, S. Krishnan, C. Agyemang, D. Ingram, R. Lascano, A. Basi, J. Gomez, J. Burks, A. Lazar, J. Ludwig

Read the abstract

Say hello to our team at booth #646

Do you have questions about Spatial Biology image analysis? Visit our friendly team at booth #646 and get the answers you need. Our experts are available to provide you with the latest insights on multiplex image analysis techniques and applications. Keep an eye out for the friendly faces – they're waiting to welcome you to our booth. 

Regan Baird, SVP, Research Commercial Strategy Deployment

Regan Baird

SVP, Research Commercial Strategy Deployment
Amanda Lowe, Managing Director, Americas

Amanda Lowe

Managing Director, Americas
Kyle R Kisiel, Vice President, New Business Sales

Kyle R Kisiel

Vice President, New Business Sales
Jim Mansfield - coloured

James R. Mansfield

SVP, Research Business Development
Dan Winkowski, Technical Sales Specialist

Dan Winkowski

Technical Sales Specialist
Fabian Schneider
Fabian Schneider
Product Manager Research

If you have a burning question you can't wait to ask at AACR, don't hesitate to get in touch with our team here.

For more information about the conference itself, visit the AACR event page.