Welcome to The Intel, the Visiopharm Newsletter that brings you our latest news and digital pathology content each month. Here are the highlights of this month:
Exciting scientific evidence with Qualitopix™
Lab Manager's article: Improving Productivity in Digital Pathology Using AI
Customer spotlight: Prof. Heather Stevenson-Lerner (University of Texas Medical Branch)
Featured publication: Chanel's poster
As always, feel free to get in touch if you have any questions or would like to book a demo. You can also check out our Resources page for the latest guides, posters and webinars.
Exciting scientific evidence with Qualitopix™
New research from UMC Utrecht uncovered unexpected IHC staining inconsistencies using Visiopharm’s Qualitopix™ software – even within the same slide – that manual assessments often miss.
The team used Qualitopix™ to continuously monitor HER2 and PD-L1 stain consistency, revealing machine-specific variations and prompting maintenance to fix this otherwise overlooked issue. This study highlights why continuous AI-based quality control is essential for accurate biomarker assessment and treatment decisions.
“With Qualitopix™ as extra quality control tool, it is much easier to detect the need for maintenance immediately, rather than awaiting the mandated time of the yearly control.”
Images taken from Qualitopix® analysis of HER2 stained HCL028 cells expressing different protein levels results reflecting different days with “strong, normal and weak” staining intensities. The AI measured differences in staining intensities for the 1+ and 2+ cores can well be seen.
Article: Improving Productivity in Digital Pathology Using AI
In the latest article published by Lab Manager, experts from Agilent, Hamamatsu, Visiopharm, PathAI, and Proscia shared transformative advancements reshaping the field.
Visiopharm's CEO, Michael Grunkin, highlighted key contributions to the workflow enabling precision pathology at scale, including:
Zero-click automation for slide and stain quality control
Advanced quantification capabilities for robust identification, classification, and measurement of microstructural content to support robust diagnostic decisions.
Interoperable plug-in architecture, which is agnostic to scanners, IMS/PACS and staining platforms to meet pathologists at any stage of their digital transformation.
We had the pleasure of speaking with Prof. Heather Stevenson-Lerner, MD, PhD, a leading liver pathologist at the The University of Texas Medical Branch, about how she uses Visiopharm software to measure the differences in immune cell populations in chronic liver diseases.
“Over the years, we’ve tried a lot of different things, and we found that Visiopharm is the best at helping us differentiate these different phenotypes within the hepatic microenvironment and these various diseases.”
Animal-free skin research model – accurately quantified
There is a critical need for robust and reproducible models in cosmetic research as alternatives to animal models.
The research team at Chanel evaluated the effectiveness of an innovative ex vivo method for maintaining human skin tissue in culture for up to 14 days, providing flexibility for studying different biological mechanisms, from short-term effects (e.g., exfoliation) to longer-term impacts (e.g., anti-aging). In a second step, they used this model to investigate the exfoliating effect of a specific lotion using Visiopharm's deep-learning analysis.
